Savage, T. M., Fortson, K. T., de Los Santos-Alexis, K., Oliveras-Alsina, A., Rouanne, M., Rae, S. S., Gamarra, J. R., Shayya, H., Kornberg, A., Cavero, R., Li, F., Han, A., Haeusler, R. A., Adam, J., Schwabe, R. F. and Arpaia, N. (2024) Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis. Immunity 57: 303–318.e6. PMID: 38309273

Savage, T.M., Vincent, R.L, Rae, S.S., Huang, L.H., Ahn, A., Pu, K., Li, F., Santos-Alexis, K.L., Coker, C., Danino, T. and Arpaia, N. (2023) Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity. Science Advances 9: 9436. PMID: 36888717

Rankin, L.C., Kaiser, K.A., de Los Santos-Alexis, K., Park, H., Uhlemann, A.C., Gray, D.H.D. and Arpaia, N. (2023) Dietary tryptophan deficiency promotes gut RORγt+Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism. Cell Reports 42: 112135. Advance online publication. PMID: 36840944

Kaiser, K.A., Loffredo, L.F., Santos-Alexis, K.D.L., Ringham, O.R., Arpaia, N. (2023) Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells. J. Exp. Med. 220: 1-20. PMID: 36534084

Gurbatri, C.R., Arpaia, N. and Danino, T. (2022) Engineering bacteria as interactive cancer therapies. Science 378: 858–864. PMID: 36423303

Filliol, A., Saito, Y., Nair, A., Dapito, D.H., Yu, L.X., Ravichandra, A., Bhattacharjee, S., Affo, S., Fujiwara, N., Su, H., Sun, Q., Savage, T.M., Wilson-Kanamori, J.R., Caviglia, J.M., Chin, L., Chen, D., Wang, X., Caruso, S., Kang, J. K., Amin, A.D., Wallace, S., Dobie, R., Yin, D., Rodriguez-Fiallos, O.M., Yin, C., Mehal, A., Izar, B., Friedman, R.A., Wells, R.G., Pajvani, U.B., Hoshida, Y., Remotti, H.E., Arpaia, N., Zucman-Rossi, J., Karin, M., Henderson, N.C., Tabas, I. and Schwabe, R.F. (2022) Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis. Nature 610: 356–365. PMID: 36198802

Harimoto, T., Hahn, J., Chen, Y.Y., Im, J., Zhang, J., Hou, N., Li, F., Coker, C., Gray, K., Harr, N., Chowdhury, S., Pu, K., Nimura, C., Arpaia, N., Leong, K.W. and Danino, T. (2022) A programmable encapsulation system improves delivery of therapeutic bacteria in mice. Nature Biotechnology 40: 1259–1269. PMID: 35301496

Affo, S., Nair, A., Brundu, F., Ravichandra, A., Bhattacharjee, S., Matsuda, M., Chin, L., Filliol, A., Wen, W., Song, X., Decker, A., Worley, J., Caviglia, J.M., Yu, L., Yin, D., Saito, Y., Savage, T., Wells, R.G., Mack, M., Zender, L., Arpaia, N., Remotti, H.E., Rabadan, R., Sims, P., Leblond, A.L., Weber, A., Riener, M.O., Stockwell, B.R., Gaublomme, J., Llovet, J.M., Kalluri, R., Michalopoulos, G.K., Seki, E., Sia, D., Chen, X., Califano, A. and Schwabe, R.F. (2021) Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell 39: 866–882. PMID: 34129825

Rouanne, M., Arpaia, N. and Marabelle, A. (2021) CXCL13 shapes tertiary lymphoid structures and promotes response to immunotherapy in bladder cancer. European Journal of Cancer 151: 245–248. PMID: 33972155

Gurbatri, C. R., Lia, I., Vincent, R., Coker, C., Castro, S., Treuting, P. M., Hinchcliffe, T.E., Arpaia N., Danino, T. (2020) Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies. Science Translational Medicine, 12. PMID: 32051224

Chowdhury, S., Castro, S., Coker, C., Hinchliffe, T.E., Arpaia, N.*, Danino, T.* (2019) Programmable bacteria induce durable tumor regression and systemic antitumor immunity. Nat. Med. 25: 1057–1063. PMID: 31270504

Kaiser, K.A. and Arpaia, N. (2018) Glycans for good. Sci. Immunol. 3. PMID: 30341146

Rankin, L.C. and Arpaia, N. (2018) Treg cells: A LAGging hand holds the double-edged sword of the IL-23 axis. Immunity 49: 201-203. PMID: 30134197

Yen, B., Fortson, K.T., Rothman, N.J., Arpaia, N.* and Reiner, S.L.* (2018) Clonal bifurcation of Foxp3 expression visualized in thymocytes and T cells. Immunohorizons 2: 119–128. PMID:29707696

Green, J.A.*, Arpaia, N.*, Schizas, M., Dobrin, A. and Rudensky, A.Y. (2017) A nonimmune function of T cells in promoting lung tumor progression. J. Exp. Med. 214: 3565–3575. PMID: 29038367

Arpaia, N., Green, J.A., Moltedo, B., Arvey, A., Hemmers, S., Yuan, S., Treuting, P.M. and Rudensky, A.Y. (2015) A distinct function of regulatory T cells in tissue protection. Cell  162: 1078–1089. PMID:26317471

Jenq, R.R., Taur, Y., Devlin, S.M., Ponce, D.M., Goldberg, J.D., Ahr, K.F., Littmann, E.R., Ling, L., Gobourne, A.C., Miller, L.C., Docampo, M.D., Peled, J.U., Arpaia, N., Cross, J.R., Peets, T.K., Lumish, M.A., Shono, Y., Dudakov, J.A., Poeck, H., Hanash, A.M., Barker, J.N., Perales, M.A., Giralt, S.A., Pamer, E.G. and van den Brink M.R. (2015) Intestinal Blautia is associated with reduced death from graft-versus-host disease. Biol. Blood Marrow Transplant 21: 1373–1383. PMID: 25977230

Arpaia, N. (2014) Keeping peace with the microbiome: acetate dampens inflammatory cytokine production in intestinal epithelial cells. Immunol. Cell Biol. 92: 561–562. PMID: 24913325

Sivick, K.E., Arpaia, N., Shu, J. and Barton, G.M. (2014) Toll-like receptor deficient mice reveal how innate immune signaling influences Salmonella virulence strategies. Cell Host and Microbe 15: 203–213. PMID: 24528866

Arpaia, N. and Rudensky, A.Y. (2014) Microbial metabolites control gut inflammatory responses. Proc. Natl. Acad. Sci. U.S.A. 111: 2058–2059. PMID: 24434557

Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., Liu, H., Cross, J.R., Pfeffer, K., Coffer, P.J. and Rudensky, A.Y. (2013) Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation. Nature 504: 451–455. PMID: 24226773

Arpaia, N. and Barton, G.M. (2013) The impact of Toll-like receptors on bacterial virulence strategies. Curr. Opin. Microbiol. 16: 17–22. PMID: 23290772

Mouchess, M.L., Arpaia, N., Souza, G., Barbalat, R., Ewald, S.E., Lau, L. and Barton, G.M. (2011) Transmembrane mutations in toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation. Immunity 35: 1–12. PMID: 22078797

Arpaia, N. and Barton, G.M. (2011) Toll-like receptors: key players in antiviral immunity. Curr. Opin. Virol. 1: 1–8. PMID: 22440908

Arpaia, N., Godec, J., Lau, L., Sivick, K.E., McLaughlin, L.M., Jones, M.B., Dracheva, T., Peterson, S.N., Monack, D.M. and Barton, G.M. (2011) TLR signaling is required for Salmonella typhimurium virulence. Cell 144: 675–688. PMID: 21376231

*contributed equally